1. Basic Research & Animal Models

Abstract Title: Recognition of human transthyretin aggregates by a novel monoclonal antibody
Author: Anabela Teixeira, i3S Porto, Maria Saraiva, i3S-Porto, Portugal

Abstract Title: Patient-specific evaluation of ATTR in cellular models derived from induced pluripotent stem cells
Author: Christoph Niemietz, Universitätsklinikum Münster

Abstract Title: Role of TTR on neuronal progenitor cells derived from induced pluripotent stem cells
Author: Christoph Niemietz, Universitätsklinikum Münster

Abstract Title: Novel role of SERPINA1 in ATTR Amyloidosis
Author: Christoph Niemietz, Universitätsklinikum Münster

Abstract Title: Development of NTLA-2001, a CRISPR/Cas9 genome editing therapeutic for the treatment of ATTR
Author: Kristy Wood, Intellia Therapeutics, USA

Abstract Title: Screening of amyloid inhibitors using a novel cell-based assay
Author: Okada Masamitsu, Department of Neurology, Kumamoto University Nagasaki

2. Cardiac Amyloidosis

Abstract Title: Hemodynamic profiles in patients with cardiac amyloidosis
Author: Franz Duca, Medical University of Vienna, Department of Internal Medicine II, Division of Cardiology

Abstract Title: Study Design and Rationale of APOLLO-B: A Study to Evaluate Patisiran in Patients with Transthyretin Amyloidosis with Cardiomyopathy
Author: John Vest, Alnylam Pharmaceuticals, Cambridge MA 02142

Abstract Title: Increased mortality associated with transthyretin cardiac amyloidosis in Afro-Caribbean patients with unexplained left ventricular hypertrophy
Author: Rishika Banydeen, University Hospital of Martinique, Guadeloupe, France

Abstract Title: TIME COURSE OF TRANSTHYRETIN REDUCTION AFTER INOTERSIN THERAPY GIVEN WITHOUT A LOADING DOSE FOR TRANSTHYRETIN AMYLOID CARDIOMYOPATHY
Author: Eva Wong, Brigham and Women’s Hospital Amyloidosis Program, Boston, MA 02115

Abstract Title: Prevalence of prior history of soft tissue structures affectation in patients with cardiac amyloidosis
Author: Raquel Vázquez-García, Complexo Hospitalario Universitario A Coruña, Spain

Abstract Title: Multimodality imaging and low intensity signals for the diagnosis of hTTR Cardiac Amyloidosis
Author: Michel SLAMA, CRMR NNERF Cardiology Department Hopital Bichat Paris France

3. Clinical Research & Therapy

Abstract Title: The Transthyretin Stabilizing Mutation (T119M) is Not Associated with Extended Lifespan or Protection Against Vascular Diseases: Analysis of the UK Biobank Cohort
Author: Margaret M. Parker, Alnylam Pharmaceuticals, Alnylam Pharmaceuticals, Cambridge MA 02142

Abstract Title: Neurofilament Light Chain (NfL) as a Potential Biomarker in Hereditary Transthyretin-Mediated (hATTR) Amyloidosis
Author: Simina Ticau, Alnylam Pharmaceuticals, Cambridge

Abstract Title: Long-Term Efficacy and Safety of Inotersen for Hereditary Transthyretin Amyloidosis: 2-Year Results From the NEURO-TTR Open-Label Extension Study
Author: Thomas Brannagan, Columbia University Medical Center, NY, NY, USA

Abstract Title: Study Design and Rationale of HELIOS-A: A Phase 3 Study to Evaluate the Efficacy and Safety of Vutrisiran in Patients with hATTR Amyloidosis
Author: John Vest, Alnylam Pharmaceuticals, Cambridge MA 02142

Abstract Title: THE BURDEN OF TRANSTHYRETIN AMYLOIDOSIS AND AMBULATORY DISABILITY ON HEALTH-RELATED QUALITY OF LIFE: RESULTS FROM AN OBSERVATIONAL STUDY
Author: Theodora Weisz, Akcea Therapeutics

Abstract Title: Impact of Apolipoprotein E on lipid nanoparticle-based  RNAi ATTR therapy
Author: Christoph Niemietz, Universitätsklinikum Münster

Abstract Title: The first six months of Patisiran in hereditary Transthyretin-amyloidosis: real-life experiences from a non-endemic center
Author: Maike F. Dohrn, RWTH Aachen University Hospital, Department of Neurology

Abstract Title: Real-life experiences with Onpattro® and Tegsedi®
Author: Anna Hüsing-Kabar, Universitätsklinikum Münster

Abstract Title: Treatment of Hereditary amyloidosis mediated by transthyretin (hATTR) in Huelva, Spain
Author: Álvaro Gragera-Martínez, Juan Ramon Jimenez University Hospital

Abstract Title: Clinical efficacy and management of thrombocytopenia and glomerulonephritis in patients with hereditary ATTR amyloidosis treated with inotersen: Results from >5 years of clinical trial and post-marketing surveillance
Author: Morie Gertz, Mayo Clinic, Rochester, MN, USA

Abstract Title: A feasibility assessment for an indirect treatment comparison of inotersen versus patisiran for the treatment of hATTR-PN
Author: Megan Lewis, Fiecon, Sandra Nestler-Parr, Akcea Therapeutics

Abstract Title: First treatment experiences with patisiran in two patients with hereditary transthyretin amyloidosis
Author: Helmar Lehmann, Department of Neurology, University Hospital Cologne, Germany

Abstract Title: A snapshot of health-related quality of life in ATTR amyloidosis in the UK
Author: Thirusha Lane, University College London, UK

Abstract Title: Presence of Transthyretin Amyloid In Carpal Tunnel Biopsies
Author: Janet Gilbertson, National Amyloidosis Centre, UCL, Division of Medicine, London, UK

Abstract Title: Case report on longterm Patisiran® Treatment
Author: Hartmut Schmidt, Universitätsklinikum Münster

Abstract Title: Gastroenterologic challenges including nutrition
Author: Jonas Wixner, Public Health and Clinical Medicine, Umeå University

4. Diagnosis, Epidemiology & Other

Abstract Title:  Enlightmen with a Care Manual of ATTR-FAP Patients and Families
Author: Chieko Kukinaka, Kumamoto University

Abstract Title: Link betwin ATTR wt versus Al-Amyloidosis.
Author: Maria del Carmen Nadal Massanet, AMILO ( Asociación Española de Amiloidosis)

Abstract Title: The disease of the 21st Century, TTR related Amyloidosis -Updates on diagnosis and treatment of cardiac amyloidosis-
Author: Ando Yukio, Nagasaki International University

Abstract Title: AmyloScan© – Development of a new screening tool for ATTRv Amyloidosis
Author: Juliane Sachau, Division of Pain Research and Therapy, Department of Neurology, University Hospital Kiel

Abstract Title: Most frequent symptoms of onset in the endemic focus of the province of Huelva
Author: Álvaro Gragera-Martínez, Juan Ramon Jimenez University Hospital

Abstract Title: Targeted genetic screening identifies pathogenic TTR alleles in almost 1% of patients with idiopathic cardiomyopathy and/or polyneuropathy
Author: Volha Skrahina, Centogene AG, Rostock

Abstract Title: ATTR Epidemiology in Huelva, Spain
Author: Álvaro Gragera-Martínez, Juan Ramon Jimenez University Hospital

Abstract Title: Epidemiological and clinical characteristics of Transthyretin familial amyloid polyneuropathy in the Republic of North Macedonia
Author: Ivan Barbov, University Clinic for neurology Skopje

Abstract Title: Founder effect and estimation of the most recent common ancestor of the Glu89Gln TTR mutation in the Bulgarian population
Author: Andrey Kirov, IMDL Genome Center “Bulgaria”, Sofia, Bulgaria

Abstract Title: Incidental finding of TTR gene variants in patients diagnosed with AL amyloidosis
Author: Dorota Rowczenio, National Amyloidosis Centre, London

Abstract Title: External quality assessment (EQA) scheme for genetic testing in ATTR amyloidosis
Author: Dorota Rowczenio, National Amyloidosis Centre, London

Abstract Title: INITIAL PATIENT MONTHLY COST OF TAFAMIDIS IN MASSACHUSETTS USA. A BARRIER TO ACCEPTANCE?
Author: Melissa Coyle, Brigham and Women’s Hospital Amyloidosis Program, Boston, MA, USA

Abstract Title: Report on ATTR-FAP International Meeting in Japan
Author: Chieko Kukinaka, Department of Nursing Faculty of Life Science Kumamoto University

Abstract Title: Sensory and motor self-rehabilitation in hereditary transthyretin amyloidosis
Author: Agnes Morier, CHU Bicêtre, Paris

Abstract Title: Burden of illness of hATTR amyloidosis on patients and caregivers
Author: Thirusha Lane, University College London, UK

ABSTRACTS: https://attrmeeting.org/wp-content/uploads/2019/09/Abstracts_grouping_23092019.pdf